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Application Specific LC Systems
Nexera FV
Taking Online Dissolution Testing Into the New Era of Ultra High Performance Chromatography Nexera FVDissolution tests are widely used in original pharmaceuticals development and quality control and for bioequivalence tests in generic drugs.
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Handheld Raman Analyzer
TacticID®-1064
The TacticID®-1064 is a field-ready handheld spectral analysis instrument designed for non-contact forensic analysis by safety personnel and first responders, including law enforcement personnel, bomb squads, customs and border patrol, hazmat technicians, and more. The TacticID®-1064 utilizes proven Raman spectroscopy, allowing users to get real-time actionable identification of unknown chemicals, explosives, narcotics, pharmaceutical drugs and many other substances while reducing operational uncertainty and response time. The TacticID®-1064 includes a comprehensive library of over 10,000 substances. In addition, users have flexibility to create their own libraries. By utilizing the 1064nm wavelength, the TacticID®-1064 avoids fluorescence, allowing users to get results in less than 1 minute even when working with tough street samples.
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ASAPrep
Compound isolation, purity analysis, and impurity analysis in pharmaceutical drug development presents increasing challenges to the industry as there is a clear need to enhance productivity and ensure compliance with evolving regulatory requirements. Such challenges are common to the development of new chemical entities, generic pharmaceutical manufacturing and contract research organizations. To help enhance productivity in compound purification and isolation Shimadzu has developed ASAPrep (Automated Scale-up from Analytical to Preparative), a unique solution to automate and optimize the purification process.
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LC/MS/MS Forensic Toxicology Database
The database includes information on drugs of abuse, hypnotics, psychotropics, pesticides, prescription drugs and natural toxins.
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Tablet Hardness Testers
Teledyne LABS offers both manual and automated tablet hardness testers. Tablet hardness testing is a method of determining mechanical properties of a drug product, typically oral dosage forms such as a solid dose tablet. Tablet breaking force (commonly called tablet hardness) is a crucial characteristic in the manufacture of solid dose formulations. Tablet hardness testing is a major step in tablet consistency and quality control.
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Compact Data Logger for Temperature
NANO-T
Compact size for portable using; integrated USB interface for a convenient connection with PC Visual alarm when temperature or humidity is out of limit Housing material is free of toxicity and halogen, which is in compliance with food and drug safety requirements Suitable for temperature data collection in narrow space
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Multi-omics Analysis Package
The Multi-omics Analysis Package, developed for metabolic engineering applications, provides the ability to automatically generate metabolic maps and perform a variety of data analysis for the vast data generated in fields like metabolomics, proteomics and flux analysis. It offers a powerful platform to support drug discovery, bioengineering and other life science research applications.
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Energy Dispersive X-ray Fluorescence Spectrometer
Pharmaceutical Elemental Impurities Analysis System
Control of Elemental Impurities in Pharmaceuticals In the pharmaceutical industry, the analysis of elemental impurities is necessary to ensure the safety of pharmaceuticals. In December 2014, the "Guideline for Elemental Impurities" (Q3D) was issued by the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH), consisting of representatives from Europe, the U.S. and Japan. In Japan, the "Guideline for Elemental Impurities in Drug Products" (PFSB/ELD Notification 0930 #4 from the Ministry of Health, Labour and Welfare) was issued, and will be applied to new drug products submitted for approval after April 1 2017. For 24 elements categorized in Class 1 to Class 3, residual quantities in pharmaceutical drug products must be controlled within permissible limits. Although ICP-AES and ICP-MS are used for precise analysis of elemental impurities, X-ray fluorescence spectrometers can be used as an alternative analysis method. This is because they can quantitatively and qualitatively analyze a variety of elements nondestructively, and without chemical pretreatment, unlike ICP-AES and ICP-MS systems. The X-ray fluorescence spectrometry has been adopted as a general method of analysis in the U.S Pharmacopeia and the European Pharmacopoeia. (USP<735>, Ph.Eur.2.2.37)
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Microcalorimeters
TA Instruments’ Isothermal Titration Calorimetry (ITC), Differential Scanning Calorimetry (DSC), and Isothermal Calorimetry systems are powerful analytical techniques for in-depth characterization of molecular binding events and structural stability. Thermodynamic binding signatures not only reveal the strength of a binding event, but the specific or nonspecific driving forces involved. Structural stability profiles from DSC reveal strengths and weaknesses in higher order structure and define the behavior of individual domains and their interactions. The TA Instruments Affinity ITC, Nano ITC and Nano DSC provide the performance, reliability and ease-of-use required for the most demanding applications in drug discovery, protein-protein interactions, structure-function characterization and more.
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Application Specific LC Systems
Co-Sense for Impurities
The FDA draft guidance, "Genotoxic and Carcinogenic Impurities in Drug Substances and Products: Recommended Approaches" prescribes permitted limits for genotoxic impurities in drug substances. These impurities demand more sensitive trace-level analysis than normal impurities. Generally, mass spectrometry methods, such as GC/MS or LC/MS, are used for the high-sensitivity analysis of impurities. However, there is increasing demand for the establishment of a high-sensitivity quantitation method using an absorbance or other conventional detector that is easy to operate and can easily apply existing LC analysis conditions.
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Aerosol Optical Tweezers
Bristol Industrial & Research Associates Ltd
Biral Manufacturers Aerosol Optical Tweezing instruments that offer the ability to study individual particles over indefinite periods. Developed in collaboration with the Bristol Aerosol Research Centre at the University of Bristol the instruments are used in research applications such as atmospheric chemistry, pharmaceutical drug development and basic aerosol research.
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Trace Evidence Workstation multi-examination
ffTATM
Powerful and versatile, the ffTA provides the forensic scientist with a range of techniques, both new and old, for the examination of trace evidence including: Glass fragments, bodily fluids, gunshot residues, drugs and illicit substances, paint chips, pigments, organic and synthetic fibres.
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Control Relays
Drexelbrook manufactures a supporting line of control relays that are developed especially for use as safe, reliable, economical original equipment components in many different types of commercial and industrial products.Designed to operate from electrodes or probes contacting conductive liquids, our control relays are ideally suited for level control applications in such products as vending, dispensing, ice-making machines, water softeners, dishwashers, and coffee makers, plus many types of operating equipment in the food, drug, dairy, brewing, distilling and chemical processing industries.
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Bottle Perpendicularity Tester
ZPY-G
Bottle Perpendicularity Tester is suitable for measuring the preform perpendicularity (deviation) of ampoules, vials, PET bottles and other bottles of drugs, food, cosmetics. According to international standards, the innovative design and the fully automated test process greatly improves the accuracy of the test.
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Pharmaceutical Analysis Contract Services
Specialist pharmaceutical analysis contract services to support development programs (R&D), regulatory submissions, GMP manufacturing and post-marketing requirements Pharmaceutical analysis contract services can play an important role in your the development process and GMP manufacturing. Concerns about drug safety, costly development programs, complex manufacturing, market demands for evidence-based data and increased regulatory requirements are all issues that can be addressed through a better understanding of your drug substance, drug product or manufacturing process which, in turn, can only be achieved through experienced analytical studies and robust analytical data.
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LC/MS/MS Method Package For Veterinary Drugs Ver. 2
*Method package including 129 veterinary drug compounds, more than 3 times as many as Ver. 1*High-speed method with just 16.5 mins detection time*Pretreatment program to improve the peak shape for polar veterinary drug compounds*Data analysis is made simple with LabSolutions Insight™
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Cobot Testing System
CT6
The CT6 cobot testing system introduces the benefits of automation to the testing of biomedical devices and components. This system pairs a collaborative robot with a 5900 or 6800 Series universal testing system to increase the efficiency of small to mid-sized testing labs that require a high degree of flexibility in their testing systems. The CT6 is designed to handle a wide range of medical components, including drug delivery, sample collection, and wound closure products.
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Isothermal Titration Calorimeters
MicroCal ITC Range
The "Gold Standard" for measuring binding affinity and stoichiometry. MicroCal ITC isothermal titration calorimeters are used to study a wide range of biomolecular interactions. The applications range from drug design to fundamental research such as the understanding and regulation of signal transduction pathways. These systems deliver direct, label free and in-solution measurements of binding affinity and thermodynamic parameters in a single experiment. They have high sensitivity, low sample consumption and options for automation to minimize ‘hands on’ time. A choice of instruments ensures that MicroCal ITC calorimeters meet the varied and demanding requirements of today’s life science laboratories.
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Dissolution Autosampler
Dissolution of tablets and capsules is essential for effective administration of therapeutic treatments. Discerning the dissolution rate of the tablet or capsule is vital. Distek's dissolution products are specifically engineered to accurately and reliably measure the rate of drug release.
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Sample Preparation Unit SPU 200i
SPUs (Sample Preparation Unit) provide a fast and easy way to recover active drug from the induction ports and/or preseparators during APSD testing.
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Medical Equipment
We develop solutions for demanding medical applications. Whether a Home Healthcare CPAP or complex Robotic Surgical System, Haydon Kerk Pittman can deploy a solution designed to your program requirements. We offer lube free systems for clean, maintenance-free operation; specialty materials for radiation, autoclaving and chemical environments; smooth and quiet operation for patient facing applications; and miniature and micro product designs for precision fluid pump and drug delivery systems.
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GC/MS Forensic Toxicological Database
The GC/MS Forensic Toxicological Database contains information for the simultaneous screening of toxicological substances including drugs of abuse, psychotropic drugs, medical drugs and pesticides. Version 2 adds 1198 compounds to the previous version for a total of 2210 compounds in the database. It also includes optimized methods for headspace analysis of alcohol and volatile toxic substances such as cyanides and azides, providing total support for GC/MS toxicology analysis.
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Microscopic Melting Point Meter
DRK8029
Shandong Drick Instruments Co., Ltd.
Determination of the melting point of the substance. Mainly used for the determination of drugs, chemicals, textiles, dyes, perfumes and other organic crystal, the microscope. Measured either by capillary method, and the slides are available - coverslip (hot stage method).
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Dissolution Testing
Agilent offers laboratories the pharmaceutical dissolution testing apparatus, dissolution accessories, and dissolution software for efficient and reliable dosage form testing. Extensive dissolution skills training is also offered to meet the needs of all busy laboratory analysts. Feel confident with Agilent dissolution testing apparatuses. All systems meet the international harmonized guidance requirements defined by USP, EP, CP, IPC, and JP for effective drug dosage form testing. Laboratory analysts can efficiently meet data integrity requirements too. Working to Title 21 Code of Federal Regulations (CFR) part 11 compliance standards is readily achieved using Agilent dissolution testing software.
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Compact Data Logger for Temperature and Humidity
NANO-TH
Compact size for portable using; integrated USB interface for a convenient connection with PC Visual alarm when temperature or humidity is out of limit Housing material is free of toxicity and halogen, which is in compliance with food and drug safety requirements Suitable for temperature and humidity data collection in narrow space
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Potentiometric Titrators
Potentiometric titrators provide results which are based on analysis methods that are highly important in the field of electrochemistry and are commonly used for the determination of different organic and inorganic ions in various areas such as process control and environmental, industrial, agricultural analysis and also medicinal drug analysis.
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Portable Mass Spectrometer
Continuity
Continuity™ - the most sensitive portable mass spectrometer designed to provide quality and reliable mass spectrometer analysis outside of the laboratory. Continuity™ was created to provide even higher sensitivity, greater specificity with built-in MS/MS, and larger mass range coverage than its ground-breaking counterpart Portability™. Like its counterpart, Continuity™ requires no sample preparation and is compatible with almost any ambient ionization source including ESI, APCI, TD-ESI, TD-APCI, and DBDI. It allows for a broad range of applications from clinical to drug to chemical and biological threats analysis. The user-friendly interface, rapid deployment, and real-time results make Continuity™ a great solution for fast, dependable, and highly sensitive field analysis for any user in any location. This potable mass spectrometer is the excellent solution for various challenging applications, including vapors/liquids/solids, CWAs/TICs, biological/biomedical, forensic, agriculture, food safety, security, and explosives.
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Leak & Seal Integrity Tester
Saicheng Leak Tester is professionally designed for the leakage tests of packages, bottles & pouches for food, drugs, medical instruments, household chemical products, cars, electronic components, stationeries and other industrial products. The instrument also can be used to test seal performance of specimens after falling and compression tests.
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Handheld Narcotics Analyzer
TruNarc™
The global drug problem is increasing, with trafficking of meth, heroin, and emerging threats like fentanyl, and carfentanil, impacting communities worldwide. Law enforcement officials need to quickly identify suspected narcotics in the field to help keep drugs, and drug dealers, off the streets. Now with the expanded v1.7 library, the Thermo Scientific™ TruNarc™ Handheld Narcotics Analyzer enables officers, customs, border control, and other personnel to scan more than 415 suspected illicit substances in a single, definitive test.
